[{"_1":2,"_68":-5,"_69":-5},"loaderData",{"_3":4,"_38":39,"_66":-5,"_67":-5},"root",{"_5":-5,"_6":-5,"_7":8,"_22":23,"_24":25,"_26":27,"_30":31,"_36":37},"user","shoppingCartId","shoppingCart",{"_9":10,"_11":12,"_13":14,"_15":16,"_17":18,"_19":20,"_21":14},"id","no-cart","count",0,"free",true,"updatedAt","2026-02-18T08:57:40.597Z","paymentGateway","STRIPE","cartItems",[],"loading","locale","en","readerTheme","system","constants",{"_28":29},"paypalClientId","AX53Cwz8jR6rVVzzZiZNWWXl0dGagi-GZrjG-S3Ua14E5nrKMn7DxDQ730O4R8LusLPp49ALn6aRVaEy","publishers",{"_32":33,"_34":35},"companies",[],"universities",[],"needsLocaleCookieSync",false,"routes/_store+/_readers+/email_author.$slug/route",{"_40":41,"_65":-5},"book",{"_9":42,"_43":44,"_45":46,"_47":48,"_49":50,"_51":52},"Z2lkOi8vbGVhbnB1Yi9TdG9yZTo6Qm9va1Byb2R1Y3QvNjYwMjQ","title","Trisomy 21 in the 21st Century","state","published","contactAuthorMethod","email","aboutText","

Trisomy 21 in the 21st Century: Navigating Challenges, Embracing Innovations, and Empowering Lives presents a comprehensive, evidence-based framework for understanding Down syndrome in our rapidly evolving healthcare and technology landscape.

This working edition synthesizes current clinical research, emerging therapeutic approaches, and AI-enhanced data analysis to provide healthcare professionals, researchers, and interdisciplinary teams with a foundational reference. Drawing from peer-reviewed literature, clinical guidelines, and stakeholder interviews, it addresses the full lifespan continuum—from early intervention through aging-related considerations including the T21-Alzheimer's connection.

Beyond traditional clinical perspectives, this framework integrates family experiences, educational innovations, and technological advances to support evidence-based decision-making. We seek feedback from the medical and research community to refine future editions and strengthen clinical utility.

","authors",[53],{"_9":54,"_55":56,"_5":57},"Z2lkOi8vbGVhbnB1Yi9TdG9yZTo6UHJvZHVjdEF1dGhvci82OTk4Ng","name","Sam Solomon",{"_58":59},"avatar",{"_60":61,"_62":63,"_64":14},"url","https://d39qdlcrvnra4b.cloudfront.net/avatars/1715050/medium/S._Solomon_Head_shot.png?1747174819","styleName","medium","exists","currentUser","routes/_store+/_layout","routes/_store+/_readers+/_layout","actionData","errors"]

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