Sources
References
Exploring the Genetic Orchestra of Cancer: The Interplay Between Oncogenes and Tumor-Suppressor Genes
https://www.mdpi.com/2072-6694/17/7/1082American Cancer Society: Oncogenes, Tumor Suppressor Genes, and DNA Repair Genes
https://www.cancer.org/cancer/understanding-cancer/genes-and-cancer/oncogenes-tumor-suppressor-genes.htmlVeryWell Health: Why Tumor Suppressor Genes are Important In Cancer
https://www.verywellhealth.com/what-are-tumor-suppressor-genes-2249209VeryWell Health: The TP53 Gene and Its Role in Cancer
https://www.verywellhealth.com/the-p53-gene-its-role-in-cancer-2249349National Library of Medicine: DNA Damage/Repair Management in Cancers
https://pmc.ncbi.nlm.nih.gov/articles/PMC7226105National Library of Medicine: Human Variation in DNA Repair, Immune Function, and Cancer Risk
https://pmc.ncbi.nlm.nih.gov/articles/PMC9354717Evading Apoptosis - Millipore Sigma: Studying Hallmarks of Cancer With Recombinant Antibodies
https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/research-and-disease-areas/cancer-research/hallmarks-of-cancer-recombinantantibodiesNational Library of Medicine: Cracking the Codes behind Cancer Cells’ Immune Evasion
https://pubmed.ncbi.nlm.nih.gov/39201585National Library of Medicine: Prevalence and role of HER2 mutations in cancer
https://pmc.ncbi.nlm.nih.gov/articles/PMC6571037BMC Molecular Center: Role of oncogenic KRAS in the prognosis, diagnosis and treatment of colorectal cancer
https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-021-01441-4National Library of Medicine: Angiogenesis: a target in solid tumors, also in leukemia?
https://pubmed.ncbi.nlm.nih.gov/22160005Cancer Research UK: Science Surgery: ‘Why do some cancers metastasize, but others don’t?’
https://news.cancerresearchuk.org/2019/11/26/science-surgery-why-do-some-cancers-metastasise-but-others-dontNational Library of Medicine: Hormone-Dependent Cancers: Molecular Mechanisms and Therapeutical Implications
https://pmc.ncbi.nlm.nih.gov/articles/PMC9818209National Library of Medicine: Inherited TP53 Mutations and the Li–Fraumeni Syndrome
https://pmc.ncbi.nlm.nih.gov/articles/PMC5378014Medline Plus: Li-Fraumeni syndrome
https://medlineplus.gov/genetics/condition/li-fraumeni-syndromeNational Library of Medicine: Oxidative Stress: Harms and Benefits for Human Health
https://pmc.ncbi.nlm.nih.gov/articles/PMC5551541National Library of Medicine: Chronic stress: a fourth etiology in tumorigenesis?
https://pmc.ncbi.nlm.nih.gov/articles/PMC12269309American Association for Cancer Research: Implementing Mutational Epidemiology on a Global Scale: Lessons from Mutographs
https://aacrjournals.org/cancerdiscovery/article-abstract/15/1/22/750850National Library of Medicine: The critical roles of somatic mutations and environmental tumor-promoting agents in cancer risk
https://pmc.ncbi.nlm.nih.gov/articles/PMC8360498National Library of Medicine: Environmental toxicants, epigenetics, and cancer
https://pmc.ncbi.nlm.nih.gov/articles/PMC4281087Science Direct: Effect of environmental exposures on cancer risk
https://www.sciencedirect.com/science/article/pii/S0160412023005287International Journal of Oncology: Role of stress in the pathogenesis of cancer (Review)
https://www.spandidos-publications.com/10.3892/ijo.2023.5572National Library of Medicine: How chronic inflammation fuels carcinogenesis as an environmental epimutagen
https://pmc.ncbi.nlm.nih.gov/articles/PMC12176710MDPI: The Role of Inflammation in Cancer: Mechanisms of Tumor Initiation, Progression, and Metastasis
https://www.mdpi.com/2073-4409/14/7/488American College of Lifestyle Medicine
https://lifestylemedicine.orgHarvard Medical School: Division of Lifestyle Medicine
https://nutrition.hms.harvard.edu/keywords12/lifestyle-medicineNational Library of Medicine: Clinical review of alkalization therapy in cancer treatment
https://pmc.ncbi.nlm.nih.gov/articles/PMC9516301MD Anderson Cancer Center: The alkaline diet: What you need to know
https://www.mdanderson.org/cancerwise/alkaline-diet—what-cancer-patients-should-know.h00-159223356.htmlScience Direct: Resting energy expenditure in cancer patients: Agreement between predictive equations and indirect calorimetry
https://www.sciencedirect.com/science/article/abs/pii/S2405457721000334Science Direct: Elevated energy expenditure in cancer patients with solid tumours
https://www.sciencedirect.com/science/article/abs/pii/027753799190050NHealthline: How Many Calories Do You Burn While Walking? https://www.healthline.com/health/calories-burned-walking
Zhao, J., et al. (2024). Glycolysis in the tumor microenvironment: a driver of cancer PMC (free full-text): https://pmc.ncbi.nlm.nih.gov/articles/PMC11199735
Ward, C., et al. (2020). The impact of tumour pH on cancer progression: strategies for PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC9400736/
Xiao, C., et al. (2022). Glycolysis in tumor microenvironment as a target to Frontiers in Cell and Developmental Biology: https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2022.1013885/
Alkaline Food Chart, Dr Mark Mincolla, PhD markmincolla.com
Fiolet et al. (2022). Association between ultra-processed food consumption and cancer risk PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC10285062
Mendes-Soares et al. (2023). The relationship between dietary inflammatory potential and cancer outcomes PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC10582578
National Cancer Institute. Aflatoxins – Cancer-causing substances https://www.cancer.gov/about-cancer/causes-prevention/risk/substances/aflatoxins
Turati, F., et al. Glycemic Index, Glycemic Load and Cancer Risk: An Updated Systematic Review and Meta-Analysis Food & Function. 2019. [PMCID PMC6835610]: https://pmc.ncbi.nlm.nih.gov/articles/PMC6835610
The Warburg Effect: How Does it Benefit Cancer Cells? PMC. March 2016: https://pmc.ncbi.nlm.nih.gov/articles/PMC4783224
Reuter, S., Gupta, S. C., Chaturvedi, M. M., & Aggarwal, B. B. (2010). Oxidative stress, inflammation, and cancer: How are they linked? Frontiers in Bioscience: https://pmc.ncbi.nlm.nih.gov/articles/PMC2990475/
National Cancer Institute. Antioxidants and Cancer Prevention (2024) https://www.cancer.gov/about-cancer/causes-prevention/risk/diet/antioxidants-fact-sheet
About the Author
Deb Brewer is a Stage 4 cancer survivor and Lifestyle Medicine practitioner who has successfully managed her cancer through lifestyle interventions. She holds certification in Nutritional Lifestyle Medicine from Harvard Medical School Executive Education and has combined her personal experience with research and training from preeminent homeopaths, naturopaths, and the American College of Lifestyle Medicine.
After her diagnosis and metastasis, Deb was not initially a candidate for chemotherapy or radiation. Through her dedicated application of lifestyle medicine principles, her lung nodules have remained stable or shrinking for 2 1/2 years, with no new growths, and her original cancer site has been clear for almost 6 years.
Deb created ReachVitality to share her knowledge and empower others facing cancer—or seeking to prevent it—by providing the tools and guidance needed to take control of their health and reach vitality.
Disclaimer
This book is not intended as a substitute for medical advice from physicians. The reader should regularly consult a physician in matters relating to his/her health and particularly with respect to any symptoms that may require diagnosis or medical attention. The information provided is based on the author’s personal experience and research and should not be considered medical advice. Always consult with qualified healthcare professionals before making changes to your health regimen, especially when dealing with cancer or other serious medical conditions.